Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic. (PDF)

The limited effectiveness of current therapies against Alzheimer’s disease (AD) highlights the need for intensifying research efforts devoted to developing new agents for preventing or retarding the disease process. During the last few years, targeting the endogenous cannabinoid system has emerged as a potential therapeutic approach to treat Alzheimer. The endocannabinoid system is composed by a number of cannabinoid receptors, including the well-characterized CB1 and CB2 receptors, with their endogenous ligands and the enzymes related to the synthesis and degradation of these endocannabinoid compounds.

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Dr. Bonni Goldstein on Clinical Applications of Medical Cannabis

Bonni Goldstein, MD is the Medical Director of Canna-Centers, a California-based medical practice devoted to educating patients about the use of cannabis for serious and chronic medical conditions. After years of working in the specialty of pediatric emergency medicine, she developed an interest in the science of medical cannabis after witnessing its beneficial effects in an ill friend.

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Patient’s Guide to CBD (download available)

The Patient’s Guide to CBD is a comprehensive resource that covers a wide range of topics, including, available forms for use, what to look for on package labels, how to read a certificate of analysis, how CBD interacts with the endocannabinoid system, the current state of research, the compound’s legal status, and how to talk to one’s doctor about CBD.

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Dr. Sanjay Gupta Reports: WEED 5: The CBD Craze

More than six years ago, Dr. Sanjay Gupta set out to investigate the science behind medical marijuana. A year later WEED, the first documentary in the award-winning series aired on CNN with an accompanying op-ed penned by Gupta: “Why I Changed my Mind on Weed.” Now, his fifth documentary WEED 5: The CBD Craze, will premiere on Sunday, September 29th at 8pm ET/PT, with Gupta returning to Colorado where he started his journey and introduced viewers for the first time to the word few could even pronounce – Cannabidiol (CBD).

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Upcoming Research: Cannabinoids’ Effects on Arthritic Pain and Ankylosing Spondylitis

Cannabinoids seem promising for treating the symptoms or progression of rheumatoid arthritis. But in the name of caution, many doctors prefer no treatment rather than trusting anecdotal reports about cannabis for arthritic pain. There’s hope that this attitude may change with upcoming research from a group of Danish scientists who recently pre-registered a double-blind randomized controlled trial of cannabinoids’ effects on arthritic pain and ankylosing spondylitis.

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Targeting Inflammation with CBD

In research published in Free Radical Biology and Medicine, scientists at the University of Mississippi medical center described not only the complexities and challenges posed by trying to specifically target oxidative stress in a variety of disease states, but also the potential benefits of using CBD to accomplish this goal.

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